To estimate the replication of the human T-cell leukemia virus type I (HTLV-I) in patients with HTLV-I-associated myelopathy (HAM), or tropical spastic paraparesis (TSP), HTLV-I DNA integrated into lymphocyte genomes was analyzed by Southern blot hybridization. HTLV-I DNA was detected in 125 (82%) o
Parkinsonism in the course of HTLV-I-associated myelopathy
✍ Scribed by Marzia Puccioni-Sohler; Regina Papais-Alvarenga; Priscila Mesquita de Souza; Silvia Curi de França; Reizer Reis Gonçalves; Steven Jacobson
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 55 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Parkinsonian syndromes may represent a complication of viral infection. Human T cell lymphotropic virus I (HTLV‐I) is a cause of a chronic myelopathy in which encephalic involvement has been also found. We report on the case of a 60‐year‐old man with HTLV‐I‐associated myelopathy, complicated with bradykinesia, resting tremor, and cogwheel rigidity. These findings suggest that parkinsonian features may represent a neurological disorder associated with HTLV‐I infection. © 2005 Movement Disorder Society
📜 SIMILAR VOLUMES
## Abstract Peripheral nerve dysfunction (PND) was found in as many as 43% of our patients with human T‐cell lymphotropic virus type I (HTLV‐I)–associated myelopathy (HAM/TSP). To evaluate the PND further we biopsied the sural nerve in 6 patients. The histological features were varying degrees of d