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Parkinson disease: analysis of mitochondrial DNA in monozygotic twins

✍ Scribed by Kösel, S.; Grasbon-Frodl, E. M.; Hagenah, J. M.; Graeber, M. B.; Vieregge, P.

Book ID
113055601
Publisher
Springer
Year
2000
Tongue
English
Weight
75 KB
Volume
2
Category
Article
ISSN
1364-6745

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## Abstract The reduced form of nicotinamide adenine dinucleotide coenzyme Q reductase (complex I) activity has recently been shown to be deficient in the substantia nigra of patients dying with Parkinson's disease. This biochemical defect is identical to that produced by the neurotoxin 1‐methyl‐4‐