A combined linkage analysis was performed on chromosome 18 data and produced modest evidence in three of four data sets for linkage of a susceptibility locus for bipolar disorder to markers on chromosome 18p. All data sets showed a preponderance of females among affected individuals. When this was t
Parental bonding in bipolar affective disorder
β Scribed by Peter R. Joyce
- Book ID
- 118388357
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 238 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0165-0327
No coin nor oath required. For personal study only.
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We combined the five chromosome 18 bipolar affective disorder data sets provided by GAW10, totaling 185 families with 3,394 individuals, and performed analysis of differential parental transmission and chromosome 18 marker allele sharing in families with transmission through fathers vs those through
reported an excess of maternal transmission in bipolar affective disorder in multiply affected families. In a sample of 130 families ascertained through a bipolar proband without regard to psychiatric family history we analysed the frequency of maternal (MAT) and paternal (PAT) transmissions, the mo