Parent of origin effects
β Scribed by A Guilmatre; AJ Sharp
- Book ID
- 110889317
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 540 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0009-9163
No coin nor oath required. For personal study only.
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## Abstract Genomic imprinting is an important epigenetic factor in complex traits study, which has generally been examined by testing for parentβofβorigin effects of alleles. For a diallelic marker locus, the parentalβasymmetry test (PAT) based on caseβparents trios and its extensions to incomplet
## Abstract Genomic imprinting refers to a parentβofβorigin specific effect on gene expression. At least 1% of genes in the human genome are modulated in this manner. We sought evidence for genomic imprinting in colorectal cancer by studying the ages at diagnosis in the offspring of 2,061 parentβch