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Parathyroid hormone fragment [3–34] stimulates protein kinase C (PKC) activity in rat osteosarcoma and murine T-lymphoma cells

✍ Scribed by Balu R. Chakravarthy; Jon P. Durkin; Raymond H. Rixon; James F. Whitfield

Book ID: 115762961
Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 623 KB
Volume: 171
Category: Article
ISSN: 0006-291X
DOI: 10.1016/0006-291x(90)90798-r

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## Abstract Membrane‐associated protein kinase C (PKC) activity in lymphocytes freshly isolated from rat spleen was stimulated by the C‐terminal parathyroid hormonerelated protein fragments, PTHrP‐(107–111) and PTHrP‐(107–139), at concentrations from 10^−3^ to 10^4^ pM. By contrast, the same concen