Acetate, the key modulator of inflammato
โ
Stuart F. W. Kendrick; Graeme O'Boyle; Jelena Mann; Mujdat Zeybel; Jeremy Palmer
๐
Article
๐
2010
๐
John Wiley and Sons
๐
English
โ 908 KB
Acute alcoholic hepatitis is characterized by disproportionate macrophage inflammatory cytokine responses to bacterial lipopolysaccharide. Lack of knowledge of the underlying mechanism has limited progress toward effective therapy. We postulated a novel mechanism by which ethanol increases histone a