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Paraplegia following intrathecal cytosine arabinoside

✍ Scribed by Jacob Zighelboim; Robert Peter Gale; Larry Wolff

Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
223 KB
Volume
43
Category
Article
ISSN
0008-543X

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Two childhood acute myelogenous leukemia (AML) patients receiving intrathecal (IT) and intravenous (IV) cytosine arabinoside (Ara-C) developed progressive ascending paralysis, resulting in death in one patient. Necropsy findings on this patient included spinal cord demyelination characteristic of Ar