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Paraoxonase-1 concentrations in end-stage renal disease patients increase after hemodialysis: Correlation with low molecular AGE adduct clearance

✍ Scribed by Alejandro Gugliucci; Krista Mehlhaff; Eriko Kinugasa; Hiroaki Ogata; Ricardo Hermo; John Schulze; Satoshi Kimura

Book ID: 116347425
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 506 KB
Volume: 377
Category: Article
ISSN: 0009-8981
DOI: 10.1016/j.cca.2006.09.028

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## Abstract **Background:** The mechanism of paraoxonase 1 (PON1) atheroprotective remains elusive. The lactonizing/lactonase activity of PON1 is gaining favor as the most significant in physiology. **Methods:** We studied 42 end-stage renal disease (ESRD) patients undergoing hemodialysis (HD) and