✦ LIBER ✦

Parametric analysis of histograms measured in flow cytometry

✍ Scribed by Dr. R. C. Mann; R. E. Hand Jr.; G. R. Braslawsky

Publisher: John Wiley and Sons
Year: 1983
Tongue: English
Weight: 534 KB
Volume: 4
Category: Article
ISSN: 0196-4763
DOI: 10.1002/cyto.990040111

No coin nor oath required. For personal study only.

✦ Synopsis

Flow cytometric histograms frequently consist of several components that show various degrees of overlap. For many types of analysis it is of great importance to decompose the original histogram into its components. To that purpose, we investigated the maximum likelihood approach in detail. It is shown that the iterative method to solve the maximum likelihood equations is well behaved for a variety of initial values. Algorithms to obtain initial values are presented, and the performance of the method is tested when applied to the analysis of DNA measurements from heterogeneous cell populations that differ with respect to DNA content.

📜 SIMILAR VOLUMES

Comments on “parametric analysis of hist

Comments on “parametric analysis of histograms measured in flow cytometry” by R.C. Mann et al

✍ F. G. Boese 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 191 KB

In a paper by R.L. Mann et al. (6), the authors dealt with a principal step in processing spectroscopic histograms. They considered the so-called mixture problem for the univariate normal case using the statistical approach. Given a histogram where the XkcR are the variate values defining the histo

Neural network analysis of DNA flow cyto

Neural network analysis of DNA flow cytometry histograms

✍ Peter M. Ravdin; Gary M. Clark; John J. Hough; Marilyn A. Owens; Dr. William L. 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 747 KB

## Abstract A pattern recognition system based on Neural Network Analysis, a form of artificial intelligence, was used to search DNA flow cytometry histograms for features that correlated with breast cancer patients' risk of relapse. DNA flow cytometry histograms and clinical followup information f

Modified histogram subtraction technique

Modified histogram subtraction technique for analysis of flow cytometry data

✍ W. Roy Overton 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 546 KB

The analysis and interpretation of DNA d

The analysis and interpretation of DNA distributions measured by flow cytometry

✍ Phillip N. Dean; Joe W. Gray; Frank A. Dolbeare 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 662 KB

Automated analysis in flow cytometry

✍ Hernani D. Cualing 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB 👁 1 views

Continuous measurement and analysis of s

Continuous measurement and analysis of staining kinetics by flow cytometry

✍ Tom Beumer; Arie Pennings; Hans Beck; Johan Wessels; Clemens Haanen; Chester Her 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 441 KB