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Comments on “parametric analysis of histograms measured in flow cytometry” by R.C. Mann et al

✍ Scribed by F. G. Boese


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
191 KB
Volume
7
Category
Article
ISSN
0196-4763

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✦ Synopsis


In a paper by R.L. Mann et al. (6), the authors dealt with a principal step in processing spectroscopic histograms. They considered the so-called mixture problem for the univariate normal case using the statistical approach.

Given a histogram where the XkcR are the variate values defining the histogram classes and the h&+ the corresponding frequencies, suppose that H stems from a sample that was drawn from a parent distribution with the mixture density beginning with an appropriate chosen vector y(O'. The authors stated correctly that the iteration 4 will converge if for any matrix norm 11 * 1) (compatible with the vector norm used in Rd) the Jacobian 9' of @ obeys 11 @'(y*) 11 < x , h < 1


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Parametric analysis of histograms measur
✍ Dr. R. C. Mann; R. E. Hand Jr.; G. R. Braslawsky 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 534 KB

Flow cytometric histograms frequently consist of several components that show various degrees of overlap. For many types of analysis it is of great importance to decompose the original histogram into its components. To that purpose, we investigated the maximum likelihood approach in detail. It is sh