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Parallel assessment of glutathione-based detoxifying enzymes, O6-alkylguanine-DNA alkyltransferase and P-glycoprotein as indicators of drug resistance in tumor and normal lung of patients with lung cancer


Book ID
122100670
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
143 KB
Volume
12
Category
Article
ISSN
0169-5002

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Parallel assessment of glutathione-based
✍ Aurelia E. Oberli-SchrΓ€mml; Franziska Joncourt; Markus Stadler; Hans-Jorg Alterm πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 French βš– 1005 KB

The levels of several potential indicators of drug resistance were measured in tumor and corresponding normal tissue of 55 untreated patients with lung cancer. The resistance parameters include glutathione (GSH) level, activities of the enzymes glutathione transferase (GST), glutathione peroxidase (