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Cytostatic drug resistance: parallel assessment of glutathione-based detoxifying enzymes, O-alkylguanine-DNA-alkyltransferase and P-glycoprotein in adult patients with leukaemia

✍ Scribed by Franziska Joncourt; Aurelia Oberli; Shelagh M. S. Redmond; Martin F. Fey; Andreas Tobler; Geoffrey P. Margison; Alois Gratwohl; Kathrin Buser; Thomas Cerny


Book ID
114713447
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
859 KB
Volume
85
Category
Article
ISSN
0007-1048

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πŸ“œ SIMILAR VOLUMES


Parallel assessment of glutathione-based
✍ Aurelia E. Oberli-SchrΓ€mml; Franziska Joncourt; Markus Stadler; Hans-Jorg Alterm πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 French βš– 1005 KB

The levels of several potential indicators of drug resistance were measured in tumor and corresponding normal tissue of 55 untreated patients with lung cancer. The resistance parameters include glutathione (GSH) level, activities of the enzymes glutathione transferase (GST), glutathione peroxidase (