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Parahydrogen-induced polarization in imaging: Subsecond 13C angiography

✍ Scribed by K. Golman; O. Axelsson; H. Jóhannesson; S. Månsson; C. Olofsson; J.S. Petersson

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
269 KB
Volume
46
Category
Article
ISSN
0740-3194

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✦ Synopsis

High nuclear spin polarization of (13)C was reached in organic molecules. Enhancements of up to 10(4), compared to thermal polarization at 1.5 T, were achieved using the parahydrogen-induced polarization technique in combination with a field cycling method. While parahydrogen has no net polarization, it has a high spin order, which is retained when hydrogen is incorporated into another molecule by a chemical reaction. By subjecting this molecule to a sudden change of the external magnetic field, the spin order is transferred into net polarization. A (13)C angiogram of an animal was generated in less than a second. Magn Reson Med 46:1-5, 2001.

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