Paragangliomas in patients with mutations of the SDHD gene
β Scribed by Carsten C. Boedeker; Hartmut P.H. Neumann; Birke Bausch; Wolfgang Maier; Gerd J. Ridder; Jorg Schipper
- Book ID
- 117399662
- Publisher
- SAGE Publications
- Year
- 2003
- Tongue
- English
- Weight
- 50 KB
- Volume
- 129
- Category
- Article
- ISSN
- 0194-5998
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Paraganglioma (PGL) is a rare disorder characterized by tumors of the head and neck region. Between 10% and 50% of cases of PGL are familial, and the disease is autosomal dominant and subject to ageβdependent penetrance and imprinting. The paraganglioma gene (__PGL1__) has been mapped t
## Abstract Hereditary paragangliomas or glomus tumors are usually benign slowβgrowing tumors in the head and neck region. The inheritance pattern of hereditary paraganglioma is autosomal dominant with imprinting. Recently, we have identified the __SDHD__ gene encoding subunit D of the mitochondria