𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Paradoxical regulation of Bcl-2 family proteins by 17β-oestradiol in human breast cancer cells MCF-7

✍ Scribed by Leung, L K; Wang, T T Y

Book ID
110002489
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
120 KB
Volume
81
Category
Article
ISSN
0007-0920

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Interleukin 6 is secreted by breast fibr
Interleukin 6 is secreted by breast fibroblasts and stimulates 17β-oestradiol oxidoreductase activity of MCF-7 cells: Possible paracrine regulation of breast 17β-oestradiol levels
✍ Eric F. Adams; B. Rafferty; M. C. White 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 472 KB

## Abstract Previous studies have demonstrated that cultured human breast fibroblasts secrete a high‐molecular‐weight polypeptide which stimulates the ability of human breast‐cancer MCF‐7 cells to convert oestrone (E1) to the biologically more active 17β‐oestradiol (E2). This effect is mediated by

Down-regulation of apoptosis-related bcl
Down-regulation of apoptosis-related bcl-2 but not bcl-xL or bax proteins in multidrug-resistant MCF-7/Adr human breast cancer cells
✍ Besim Ogretmen; Ahmad R. Safa 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 797 KB

Recent studies have shown that high levels of the apoptosisrelated proteins bcl-2 and bcl-x, increase, while over-expression of bcl-x, or bax decreases, resistance to drugs that induce apoptosis in some human cancer cells. In the present report, we investigated whether expression of these apoptosis-

Comparison of the global gene expression
Comparison of the global gene expression profiles produced by methylparaben, n-butylparaben and 17β-oestradiol in MCF7 human breast cancer cells
✍ D. Pugazhendhi; A. J. Sadler; P. D. Darbre 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 509 KB

## Abstract Since the alkyl esters of __p__‐hydroxybenzoic acid (parabens) can be measured intact in the human breast and possess oestrogenic properties, it has been suggested that they could contribute to an aberrant burden of oestrogen signalling in the human breast and so play a role in the risi