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Paradoxical effects of insulin on cardiac L-type calcium current and on contraction at physiological temperature

✍ Scribed by V. K. Pabbathi; M. S. Suleiman; J. C. Hancox


Publisher
Springer
Year
2004
Tongue
English
Weight
181 KB
Volume
47
Category
Article
ISSN
0012-186X

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The effects of quercetin, a natural polyphenolic compound, on voltage-dependent L-type Ca(2+) current (I(Ca,L)) in rat pituitary GH(3) cells were investigated with the aid of the whole-cell voltage-camp technique. Quercetin (0.5-200 microM) stimulated I(Ca,L) in a concentration-dependent manner. The