Trestatin (Ro 9-0154), a new specific alpha-amylase inhibitor of microbial origin, was tested in six normal subjects and seven Type 2 (non-insulin-dependent) diabetic patients. In normal subjects the maximal increases in blood glucose following a 115-g starch meal were 2.19 +/- 0.57 mmol/l (mean +/-
✦ LIBER ✦
The effects of glucose-dependent insulinotropic polypeptide infused at physiological concentrations in normal subjects and Type 2 (non-insulin-dependent) diabetic patients on glucose tolerance and B-cell secretion
✍ Scribed by I. R. Jones; D. R. Owens; A. J. Moody; S. D. Luzio; T. Morris; T. M. Hayes
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 601 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0012-186X
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The sympathetic nervous system may contribute to excessive hepatic glucose output in Type 2 (non-insulin dependent) diabetes mellitus and could be implicated in the interrelated problem of hypertension. The aim of these studies was to determine whether subjects with Type 2 diabetes had normal sensit