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Paradoxical biological effects of overexpressed insulin-like growth factor-1 receptors in chinese hamster ovary cells

✍ Scribed by Hisanori Kato; Teresa N. Faria; Bethel Stannard; Rachel Levy-Toledano; Simeon I. Taylor; Charles T. Roberts Jr.; Derek Leroith


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
932 KB
Volume
156
Category
Article
ISSN
0021-9541

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## Abstract WWP1, a HECT type E3 ubiquitin ligase frequently amplified and overexpressed in breast cancer, has the potential to become a useful clinical biomarker and therapeutic target in breast cancer. Here, we performed immunohistochemical staining in formalin‐fixed and paraffin‐embedded tissue