“Paradoxical” analgesia induced by naloxone and naltrexone
✍ Scribed by Janet D. Greeley; A. D. Lê; Constantine X. Poulos; Howard Cappell
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 450 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The capacity of the specific narcotic antagonists naltrexone and naloxone to block the discriminative effects produced by morphine in the rat were evaluated using a two-choice, discrete-trial avoidance task. The antagonists produced a dose-dependent and time-dependent blockade of morphine's effects
The crystal structures of the analgesic compounds anhydrous naloxone and naltrexone hydrochloride were determined ab initio from high resolution laboratory X-ray powder diffraction data. Both compounds crystallize in the orthorhombic space group P2 1 2 1 2 1 with lattice parameters of a ¼ 14.6588(10