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Paradigms and paradoxes: Mechanisms for possible enhanced biological activity of bilaterally symmetrical chemicals

โœ Scribed by Alexander Greer; Orrette R. Wauchope; Nicola S. Farina; Paul Haberfield; Joel F. Liebman


Publisher
Springer
Year
2006
Tongue
English
Weight
260 KB
Volume
17
Category
Article
ISSN
1040-0400

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A reaction of 4-acetoxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one with DNA and nucleotldes was described. The N4 posltlon of the benzoxazlnone reacted with the C8 position of the guanlne residue of DNA and guanyllc acid. A group of 1,4-benzoxazln-3-ones was isolated from Job's tears, rye, wheat, and cor