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Paracrine activation of extracellular signal-regulated kinase in a simple in vitro model of wounded osteoblasts

✍ Scribed by R.W Katz; S.Y Teng; S Thomas; R Landesberg


Book ID
117807700
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
314 KB
Volume
31
Category
Article
ISSN
8756-3282

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Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) produced by osteoblasts play an essential role in bone remodeling. Hence, these proteins could provide an interesting means by which mechanical loading leads to adaptation of bone. Here, we examined the effect of st