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Papillomavirus E2 induces p53-independent apoptosis in HeLa cells

✍ Scribed by Desaintes, Christian; Goyat, Sylvain; Garbay, Serge; Yaniv, Moshe; Thierry, Françoise


Book ID
110062233
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
353 KB
Volume
18
Category
Article
ISSN
0950-9232

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## Abstract Exposure of human HeLaS~3~ cervix carcinoma cells to high doses of conventional cytostatic drugs, e.g. cisplatin (CP) strongly inhibits their proliferation. However, most cytostatic agents are genotoxic and may generate a secondary malignancy. Therefore, therapeutic strategy using alter