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p53-independent pRB degradation contributes to a drug-induced apoptosis in AGS cells

โœ Scribed by JIN, Yan; LEUNG, Wai Keung; SUNG, Joseph Jao-Yiu; WU, Jia Rui


Book ID
110020671
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
673 KB
Volume
15
Category
Article
ISSN
0007-0610

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## BACKGROUND. Apoptosis is induced by various anticancer agents or radiation through the tumor suppressor gene p53-dependent pathway and is also induced by other factors, including transforming growth factor-PI (TGF-0,). In this study, the authors investigated whether TGF-0, would induce apoptosi