The thiol protease papain catalyses the transfer of the Cbz-Gly moiety from the donor substrate Cbz-Gly-OMe to the amino group of various a-hydroxyand a-keto-amines, providing a new route to peptide isosteres. Isosteres of natural peptides, especially of dipeptides, are valuable building blocks for
โฆ LIBER โฆ
Papain catalyzed synthesis of unsymmetric cystine peptides
โ Scribed by Dar-Fu Tai; Chiu-Eh Chen; Ching-Chong Huang; Hui-Yao Huang
- Book ID
- 104634384
- Publisher
- Springer Netherlands
- Year
- 1993
- Tongue
- English
- Weight
- 228 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0141-5492
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