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Panniculitis in alpha-1 antitrypsin deficiency treated with enzyme replacement

โœ Scribed by Jonathan M. Olson; Erin C. Moore; Mark A. Valasek; Lisa H. Williams; Jay C. Vary

Book ID
116587852
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
857 KB
Volume
66
Category
Article
ISSN
1097-6787

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Severe panniculitis caused by homozygous
Severe panniculitis caused by homozygous ZZ ฮฑ1-antitrypsin deficiency treated successfully with human purified enzyme (Prolastinยฎ)
โœ M.M.U. Chowdhury; E.J. Williams; J.S. Morris; B.J.M. Ferguson; A.D. McGregor; A. ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 93 KB

Severe panniculitis caused by alpha1-antitrypsin deficiency is very rare even though the ZZ phenotype occurs in 1 : 3500 of the population of northern Europe. We describe a 33-year-old woman with rapidly progressing panniculitis and extensive skin necrosis with multiple life-threatening complication