Pankreaslipase vermitteltes Drug Delivery mit Glycerid-Arzneistoff Prodrugs

Synthesis and in vitro Evaluation of 4-(

Synthesis and in vitro Evaluation of 4-(2-Glyceryl)butyric Acid: A Glyceride Mimic for Drug Delivery via Drug-Lipid Conjugates. Synthese und in vitro Charakterisierung der 4-(2-Glyceryl)buttersäure: Ein Glyceridanalogon für “Drug Delivery” mittels Arzneistoff-Lipid Konjugaten

✍ Gerhard K. E. Scriba 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 226 KB 👁 2 views

There has been some evidence that mixed triglycerides formed from coupling of drugs to diglycerides exhibit physicochemical and absorption as natural Wiglycerides. Drugs which lack carboxyl groups, allowing the direct formation of an ester bond with a diglyceride, can be bound via spacers such as su