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Pancreatic Stellate Cells Increase the Invasion of Human Pancreatic Cancer Cells through the Stromal Cell-Derived Factor-1/CXCR4 Axis

✍ Scribed by Gao, Zhenjun; Wang, Xingpeng; Wu, Kai; Zhao, Yan; Hu, Guoyong


Book ID
122476678
Publisher
S. Karger AG
Year
2010
Tongue
English
Weight
180 KB
Volume
10
Category
Article
ISSN
1424-3903

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## Abstract The hypoxic environment in tumor is reported to play an important role in pancreatic cancer progression. The interaction between stromal and cancer cells also contributes to the malignant behavior of pancreatic cancer. In the present study, we investigated whether hypoxic stimulation af