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The Expression and Role of Stromal Cell–derived Factor-1α–CXCR4 Axis in Human Dental Pulp

✍ Scribed by Long Jiang; Ya-Qin Zhu; Rong Du; Ying-Xin Gu; Lie Xia; Feng Qin; Helena H. Ritchie


Book ID
116677191
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
526 KB
Volume
34
Category
Article
ISSN
0099-2399

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Stromal cell-derived factor-1 (SDF-1) is a CXC chemokine produced by stromal cells that acts as a chemoattractant for human CD34 + progenitor cells. We investigated the expression of CXCR4, the receptor for SDF-1, on CD34 + cells from different hematopoietic sites and developmental stages. CXCR4 was