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Pancreatic Secretory Trypsin Inhibitor 1 Reduces the Severity of Chronic Pancreatitis in Mice Over-Expressing Interleukin-1β in the Pancreas

✍ Scribed by Joelle Romac; Rafiq A. Shahid; Christoph B. Westphalen; Timothy C. Wang; Rodger A. Liddle


Book ID
119432359
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
44 KB
Volume
140
Category
Article
ISSN
0016-5085

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## Communicated by Richard G.H. Cotton Mutations in the serine protease inhibitor Kazal type 1 gene (SPINK1) encoding pancreatic secretory trypsin inhibitor (PSTI) have recently been found to be associated with chronic pancreatitis. Nevertheless, knowledge of severe mutations is particularly scarc