Pancreatic pathology in type 1 diabetes
β Scribed by Alan K. Foulis
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 23 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0146-6615
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## Abstract ## Objective The contribution of innate immunity responsible for betaβcell destruction in fulminant type 1 diabetes (FT1D) and slowly progressive insulinβdependent diabetes mellitus (SPIDDM) is unclear. ## Research Design and Methods Isletβcell expression of Tollβlike receptors (TLRs
Needle phobia in patients with Type 1 (insulin-dependent) diabetes mellitus is difficult to manage. We report a case of long-standing needle phobia in a patient with 33 years of Type 1 diabetes mellitus who has developed very few vascular complications. Further studies are required to identify the p
Various environmental triggers, e.g. certain viruses and dietary factors, are thought to initiate the autoimmune process, leading to the destruction of pancreatic beta-cells and consequent Type 1 diabetes. A genetic predisposition is another prerequisite allowing the autoimmune process to progress.