NGF induces apoptosis in a human neurobl
NGF induces apoptosis in a human neuroblastoma cell line expressing the neurotrophin receptor p75NTR
โ
P. Kuner; C. Hertel
๐
Article
๐
1998
๐
John Wiley and Sons
๐
English
โ 162 KB
๐ 2 views
Nerve growth factor (NGF) has been demonstrated to support survival and differentiation of neuronal cells. Recently, a role of NGF in neuronal apoptosis has been suggested. NGF binds to tropomyosin receptor kinase A (TrkA) and to 75-kDa NGF receptor (p75 NTR ). TrkA is responsible for differentiatio