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Palmar-Plantar Erythrodysesthesia Associated with Scrotal and Penile Involvement with Capecitabine

✍ Scribed by Christy M. Sapp; Philip DeSimone

Book ID
119935082
Publisher
CIG Media Group, LP.
Year
2007
Tongue
English
Weight
471 KB
Volume
6
Category
Article
ISSN
1533-0028

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The limiting toxicity of low dose continuous infusion 5-fluorouracil (200-300 mg/m2/day) is often palmar-plantar erythrodysesthesia (PPE). PPE developed in 16/25 patients (exact 95% confidence interval of 42%-82%) with metastatic colon cancer enrolled in a phase II trial. In this trial, 5-FU was giv