Palladium(II) compounds with potential antitumour properties and their platinum analogues: a comparative study of the reaction of some orotic acid derivatives with DNA in vitro

A study of some orotic acid derivatives

A study of some orotic acid derivatives and analogues by Hückel's method of molecular orbitals: II. Analogues of the orotic acid in the reaction with phosphoribosyl-pyrophosphate

✍ Evgeny Golovinsky; Jose Kaneti; Ivan Yukhnovsky; Dobri Genchev 📂 Article 📅 1970 🏛 Elsevier Science 🌐 English ⚖ 180 KB

The indexes of the electronic structure and the steric complementarity were used to propose a number of compounds, theoretically able to react with the phosphoribosylpyrophosphate (PRPP) on the basis of the hypothetical model of the active site of the orotidine-5'-monophosphate pyrophosphorylase sug