Palladium(0)-catalyzed allylation of highly acidic and non-nucleophilic arenesulfonamides, sulfamide, and cyanamide. I.
✍ Scribed by Sílvia Cerezo; Jordi Cortés; Marcial Moreno-Mañas; Roser Pleixats; Anna Roglans
- Book ID
- 104208951
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 992 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0040-4020
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Palladium(0)-Catalyzed Allylation of Highly Acidic and Non-Nucleophilic Arenesulfonamides, Sulfamide, and Cyanamide. Part 2. Formation of Medium and Large Heterocycles. -Reactions of the title substrates, carried out in the preceding paper with monoallylic carbonates, are now investigated with ally
## Matrix -assisted laser desorption/ionization time-of-flight mass spectrometry allowed the direct determination of the extent of macrocyclic and linear oligomer formation in the palladium(0)-catalyzed allylation of highly acidic and non-nucleophilic arenesulfonamides, sulfamide, and cyanamide. P
Recently, we reported an efficient palladium(0) catalyzed allylation of a non-stabilized nucleophile, lithium enolate of ethyl isobutyrate 2a, with monoepoxide of isoprene la, as a first step in the total synthesis of epiilludol (scheme 1).] The synthetic value of the regio-and stereoselective allyl