✦ LIBER ✦

Application of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry to the structure determination of medium and large macrocycles formed by palladium(0)-catalyzed allylation of arenesulfonamides, sulfamide, and cyanamide

✍ Scribed by Sílvia Cerezo; Jordi Cortés; David Galvan; Juan-Manuel López-Romero; Marcial Moreno-Mañas; Roser Pleixats; Francesc X. Avilés; Francesc Canals; Anna Roglans

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 95 KB
Volume: 13
Category: Article
ISSN: 0951-4198
DOI: 10.1002/(sici)1097-0231(19991215)13:23<2359::aid-rcm799>3.0.co;2-9

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✦ Synopsis

Matrix

-assisted laser desorption/ionization time-of-flight mass spectrometry allowed the direct determination of the extent of macrocyclic and linear oligomer formation in the palladium(0)-catalyzed allylation of highly acidic and non-nucleophilic arenesulfonamides, sulfamide, and cyanamide. Palladium-containing 15membered-ring macrocyclic compounds gave unusual [M À H] ions besides [M Na] and [M K] adducts.