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Palladium-Mediated Asymmetric Synthesis of Cis-3,6-Disubstituted Cyclohexenes. A Short Total Synthesis of Optically Active (+)-.gamma.-Lycorane

✍ Scribed by Yoshizaki, Hiroki; Satoh, Hisao; Sato, Yoshihiro; Nukui, Seiji; Shibasaki, Masakatsu; Mori, Miwako


Book ID
125980687
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
800 KB
Volume
60
Category
Article
ISSN
0022-3263

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A novel method for the asymmetric synthe
✍ Tsuyoshi Satoh; Masaaki Yoshida; Yasuhiro Takahashi; Hiroyuki Ota πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 English βš– 411 KB

Enantiomerically pure 1-chlorovinyl p-tolyl sulfoxides having two different substituents at the 2-position were synthesized from unsymmetrical ketones and (R)-(-)-chloromethyl p-tolyl sulfoxide in three steps. Treatment of the 1-chlorovinyl p-tolyl sulfoxides with cyanomethyllithium at -78Β°C to room