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A Palladium(II)-Catalyzed Construction of .alpha.-Methylene-.gamma.-butyrolactones in Optically Active Form. Total Synthesis of (-)-Methylenolactocin

โœ Scribed by Zhu, Guoxin; Lu, Xiyan


Book ID
125929783
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
334 KB
Volume
60
Category
Article
ISSN
0022-3263

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A palladium-catalyzed construction of en
โœ Guoxin Zhu; Xiyan Lu ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 381 KB

Optically active 13,y-disubstituted-ct-methylene-y-butyrolactones were synthesized by palladium(II)-catalyzed cyclization reactions of homochiral allylic 2-alkynoates. The reaction was applied to the total synthesis of methylenolactocin in both enantiomeric forms. G. ZHU and X. Lu our work we develo