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Palladium-Catalyzed N-Demethylation/N-Acylation of Some Morphine and Tropane Alkaloids

✍ Scribed by Robert J. Carroll; Hannes Leisch; Eric Scocchera; Tomas Hudlicky; D. Phillip Cox


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
226 KB
Volume
350
Category
Article
ISSN
1615-4150

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ChemInform Abstract: Application of Pall
✍ B. A. ANDERSON; L. M. BECKE; R. N. BOOHER; M. E. FLAUGH; N. K. HARN; T. J. KRESS 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Application of Palladium(0)-Catalyzed Processes to the Synthesis of Oxazole-Containing Partial Ergot Alkaloids. -A novel palladium(0)and copper(I)-cocatalyzed cyanation is developed to provide efficient and reproducible access to the key intermediate (V). The desired alkaloid (VIII) is obtained by c