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Palladium-catalyzed N-allylation of anilines by direct use of allyl alcohols in the presence of titanium(IV) isopropoxide

✍ Scribed by Shyh-Chyun Yang; Wen-Hung Chung


Book ID
108387289
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
190 KB
Volume
40
Category
Article
ISSN
0040-4039

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Palladium-Catalyzed Etherification of Allyl Alcohols Using Phenols in the Presence of Titanium(IV) Isopropoxide. -It offers a convenient method to prepare allyl aryl ethers. However, starting from the phenol derivative (VII) C-allylated instead of O-allylated products are obtained.

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N-Allylation of anilines using allylic alcohols directly to give monoallylic anilines selectively in high yields has been realized by employing palladium acetateΒ±triphenylphosphine as the catalyst. Palladiumcatalyzed one-pot cyclization of 2-aminophenols with 2-butene-1,4-diol leads to 3,4-dihydro-2