Direct palladium-catalyzed selective monoallylation of anilines using allylic alcohols

✍ Scribed by Shyh-Chyun Yang; Chia-Lin Yu; Yan-Chiu Tsai

• Book ID: 104210751
• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 195 KB
• Volume: 41
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)01171-0

✦ Synopsis

N-Allylation of anilines using allylic alcohols directly to give monoallylic anilines selectively in high yields has been realized by employing palladium acetate±triphenylphosphine as the catalyst. Palladiumcatalyzed one-pot cyclization of 2-aminophenols with 2-butene-1,4-diol leads to 3,4-dihydro-2-vinyl-2H-1,4-benzoxazines.