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Palladium-Catalyzed Intramolecular Trapping of the Blaise Reaction Intermediate for Tandem One-Pot Synthesis of Indole Derivatives

✍ Scribed by Kim, Ju Hyun; Lee, Sang-gi

Book ID
127213028
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
934 KB
Volume
13
Category
Article
ISSN
1523-7060

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## Abstract A robust one‐pot process has been developed for the synthesis of a variety of polycyclic indole skeletons __via__ a consecutive sequence of hydroamidation and palladium‐catalyzed annulation, from inexpensive 2‐chloroanilines bearing tethered acetylenes.