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Palladium-catalyzed cross-coupling of unsaturated phenols with vinylic halides and triflates

โœ Scribed by Richard C. Larock; Hoseok Yang; Paola Pace; Sandro Cacchi; Giancarlo Fabrizi


Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
210 KB
Volume
39
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


The palladium-catalyzed cross-coupling of o-allylic and o-vinylic phenols with vinylic halides and triflates produces substituted dihydrobenzopyrans and dihydrobenzofurans respectively in good to high yields.


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Synthesis of oxygen heterocycles via Pd-
โœ R.C. Larock; H. Yang; P. Pace; K. Narayanan; C.E. Russell; S. Cacchi; G. Fabrizi ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 835 KB

The palladium-catalyzed cross-coupling of o-allytic and o-vinylic phenols with vinylic halides and triflates produces substituted dihydrobenzopyrans and dihydrobenzofurans respectively in good to high yields. The proposed mechanism involves vinylpalladium addition to the olefin, rearrangement to a g