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Palladium-Catalyzed Coupling of Haloalkynes with Allyl Acetate: A Regio- and Stereoselective Synthesis of ( Z )-β-Haloenol Acetates

✍ Scribed by Chen, Xiaoyi; Chen, Dongxu; Lu, Zenghui; Kong, Lichun; Zhu, Gangguo


Book ID
120236016
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
849 KB
Volume
76
Category
Article
ISSN
0022-3263

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Acelates derived from a variety of the Baylis-Hillman products undergo reduction with HCOOH in the presence of Et.~N, Pd(OAc)2, and dppe (or tri-isepropylphosphite) to yield the corresponding trisubstituted Z-otefins in good yields displaying high regio and stereoselectivity.