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Palladium-Catalyzed Carbonylations of Aryl Bromides using Paraformaldehyde: Synthesis of Aldehydes and Esters

โœ Scribed by Natte, Kishore; Dumrath, Andreas; Neumann, Helfried; Beller, Matthias


Book ID
127036914
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
542 KB
Volume
53
Category
Article
ISSN
0044-8249

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Aliphatic linear and a-branched aldehydes efficiently undergo arylation at the a-position upon treatment with aryl bromides using an appropriate palladium catalyst system that is capable of overcoming aldol condensation of the substrates.