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Palladium catalysed intramolecular coupling of aryl and benzylic halides and related tandem cyclisations. A simple synthesis of hippadine.

โœ Scribed by Ronald Grigg; Andrew Teasdale; Visuvanathar Sridharan


Book ID
108381441
Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
192 KB
Volume
32
Category
Article
ISSN
0040-4039

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The aryl-benzyl cross-coupling in the lm~atce of copper., nickel-and I~\_n~\_'um-calalysts has been investigated with a number of chlorine-and methyl-substituted arylmeta/comlmmsds ArM (M= MgBr, ZnCI) amt (substituted) benzylic halides A~CH2X. The results have beca applied in the selective synthesis