Palladium-catalysed amination of halopyridines on a KF-alumina surface
β Scribed by Basudeb Basu; Satadru Jha; Niranjan K. Mridha; Md.Mosharef H. Bhuiyan
- Book ID
- 104252103
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 324 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Palladium-catalysed C-N hetero cross-coupling reactions between bromopyridines and amines (both primary and secondary) can be efficiently performed on a KF-alumina (basic) surface, thus negating the use of strong bases such as sodium tert-butoxide. The reaction conditions are optimised with reference to catalytic systems, solvents and the surface.
π SIMILAR VOLUMES
A range of conjugated polyaryls has been synthesized through one-pot microwave assisted palladium-catalyzed consecutive Suzuki coupling reactions on a KF-alumina surface with notable features including rapid reaction times, solvent-free conditions, high yields, atom economic and air-insensitive reac