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Palindromic AT-rich repeat in the NF1 gene is hypervariable in humans and evolutionarily conserved in primates

✍ Scribed by Hidehito Inagaki; Tamae Ohye; Hiroshi Kogo; Kouji Yamada; Hiroe Kowa; Tamim H. Shaikh; Beverly S. Emanuel; Hiroki Kurahashi

Book ID
102859522
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
605 KB
Volume
26
Category
Article
ISSN
1059-7794

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✦ Synopsis

Communicated by

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## Communicated by Georgia Chenevix-Trench Mutations in the RB1 gene are associated with retinoblastoma, which has served as an important model for understanding hereditary predisposition to cancer. Despite the great scrutiny that RB1 has enjoyed as the prototypical tumor suppressor gene, it has ne