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An isochore transition zone in the NF1 gene region is a conserved landmark of chromosome structure and function

✍ Scribed by Claudia Schmegner; Anke Berger; Walther Vogel; Horst Hameister; Günter Assum

Book ID
116981438
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
251 KB
Volume
86
Category
Article
ISSN
0888-7543

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While screening for new mutations in the HEXB gene, which encodes the beta-subunit of beta-hexosaminidase, a TG deletion (deltaTG) was found in the 3' untranslated region (3'UTR) of the gene, 7 bp upstream from the polyadenylation signal. Examination of DNA samples of 145 unrelated Argentinean indiv