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Pacemaker shift in the sino-atrial node during vagal stimulation

โœ Scribed by L. N. Bouman; E. D. Gerlings; P. A. Biersteker; F. I. M. Bonke


Publisher
Springer
Year
1968
Tongue
English
Weight
669 KB
Volume
302
Category
Article
ISSN
0031-6768

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We have investigated the action of 9-amino-1, 2, 3, 4-tetrahydroacridine (THA) on the pacemaker current If in rabbit sino-atrial node myocytes and in canine Purkinje fibers. THA at concentrations in the range 3-300 microM blocked If in a voltage-independent manner, as revealed by measurements on the