𝔖 Bobbio Scriptorium
✦   LIBER   ✦

PACAP activates Rac1 and synergizes with NGF to activate ERK1/2, thereby inducing neurite outgrowth in PC12 cells

✍ Scribed by Yoshiyuki Sakai; Hitoshi Hashimoto; Norihito Shintani; Hironori Katoh; Manabu Negishi; Chihiro Kawaguchi; Atsushi Kasai; Akemichi Baba


Book ID
116753019
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
479 KB
Volume
123
Category
Article
ISSN
0169-328X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Activation of ERK1 and ERK2 is required
✍ Jennifer L. Walowitz; Jerome A. Roth πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 131 KB πŸ‘ 2 views

Mn 2Ψ‰ treatment has been shown to promote neurite outgrowth in rat pheochromocytoma (PC12) cells in a time-and dose-dependent manner. This process is mediated through the interactions of extracellular matrix (ECM) proteins and integrin receptors. Studies were performed to determine whether the phosp

Presenilin-1 mutation alters NGF-induced
✍ Katsutoshi Furukawa; Qing Guo; Gerard D. Schellenberg; Mark P. Mattson πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 126 KB

Mutations in the presenilin-1 (PS-1) gene are responsible for many cases of autosomal dominant earlyonset inherited Alzheimer's disease (AD). PS-1 is expressed in neurons where it is localized primarily to the endoplasmic reticulum (ER); the normal function of PS-1 and its pathogenic mechanism in AD